In Jerusalem, an American archaeologist working on Project Year Zero -- the search for the historical Jesus -- crosses the line between science and theft when he helps plunder an old Roman landfill beneath the crucifixion grounds known as Golgotha. Nathan Lee Swift's crime will have devastating consequences. When an ancient relic is opened on the black market, a two-thousand-year-old plague is unleashed -- and the dying begins.

As the pestilence threatens to wipe out humanity, he finds a chance for redemption -- by finding the cure. Skirting the edges of civilization, Nathan Lee sets out to find his younger daughter and travels to Los Alamos, where a desperate tactic has been adopted: the use of human lab rats cloned from Project Year Zero remains. Now Nathan Lee will come face-to-face with one special cloned human who may hold the key to salvation -- in more ways than one. Patient Zero claims to remember who he is....

And his name is Jesus Christ.